Detailed Gabapentin dosage information for adults and children. Includes dosages for Restless Legs Syndrome, Epilepsy and Postherpetic Neuralgia; plus renal, liver and dialysis adjustments. If you’ve been prescribed gabapentin, Horizant, or Gralise, taking your medication correctly is vital to getting the most out of it. And using the correct dosage will help you minimize, or avoid, side effects. In this guide, we’ll review common gabapentin dosages. Gabapentin starting doses typically range from 300 to 900mg daily, divided into 2 to 3 doses. The maximum daily dose is 3,600mg for most conditions, with careful monitoring required. Dose titration should occur gradually over 3 to 14 days to minimize side effects. Medscape - Seizure dosing for Neurontin, Gralise (gabapentin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost. Most people need 1 to 2 weeks of regular dosing for the full effect to build up. How long does it take for gabapentin to work? Gabapentin can start working for pain after 1 week in some people, but usually takes several weeks to reach its full effect. Patients 12 years of age and older: starting dose is 300 mg three times daily; may be titrated up to 600 mg three times daily. Gabapentin is used to help control partial seizures (convulsions) in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it.